Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL30870384 | 0.91 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1BLM | |
| Succinamide SCHEMBL27602217 | 0.91 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1BLM | |
| Succinamide SCHEMBL1864469 | 0.91 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1BLM | |
| SCHEMBL36056 | 0.91 | — | — | |
| Succinamide SCHEMBL27602218 | 0.91 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1BLM | |
| Ammonia Solution, Strong SCHEMBL30458050 | 0.88 | — | — | |
| Hydrogen Sulfide SCHEMBL419096 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL3361793 | 0.88 | — | — | |
| Charcoal, Activated SCHEMBL6627367 | 0.88 | — | — | |
| SCHEMBL27774324 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1594284-A | Enzyme-linked clenbuterol and method for producing same | UNIV SHANGHAI (CN) | 2005-03-16 | — | — | CN | disclosed |