⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17477697 | 0.80 | — | — | |
| SCHEMBL1371544 | 0.78 | — | — | |
| SCHEMBL10904536 | 0.78 | — | — | |
| SCHEMBL19291928 | 0.75 | TSHR (0.48) | — | |
| SCHEMBL5138836 | 0.73 | — | — | |
| SCHEMBL13494737 | 0.73 | CYP1A2 (0.39) | — | |
| SCHEMBL20637947 | 0.73 | CYP1A2 (0.39) | — | |
| SCHEMBL7794827 | 0.72 | — | — | |
| SCHEMBL23065807 | 0.69 | CYP1A2 (0.36) | — | |
| SCHEMBL8724779 | 0.69 | GGT1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108516982-A | Method for preparing rifampicin by using microchannel reaction device | 南京工业大学 | 2018-09-11 | — | — | CN | claimed |
| CN-106749326-A | Method for continuously producing and preparing rifampicin from rifamycin S sodium salt | 南京工业大学 | 2017-05-31 | — | — | CN | claimed |
| CN-106632394-A | Method for preparing rifampicin by using kettle type reaction device and microchannel reaction device for series reaction | 南京工业大学 | 2017-05-10 | — | — | CN | claimed |
| CN-103951677-B | The preparation method of rifapentine | SICHUAN LONG MARCH PHARMACEUTICAL CO., LTD. (CN) | 2016-04-06 | — | — | CN | claimed |
| CN-103951677-A | Preparation method of rifapentine | SICHUAN LONG MARCH PHARMACEUTICAL CO LTD | 2014-07-30 | — | — | CN | claimed |
| CN-101486716-B | Preparation of rifampin | LI XUE | 2011-01-26 | — | — | CN | claimed |
| CN-101486716-A | Preparation of good quality benemicin | LI XUE (CN) | 2009-07-22 | — | — | CN | claimed |
| CN-100383143-C | One-pot processing method for synthesizing rifampicin | LI XUE (CN) | 2008-04-23 | — | — | CN | claimed |
| CN-1690059-A | One-pot processing method for synthesizing rifampicin | XUE LI (CN) | 2005-11-02 | — | — | CN | claimed |
| CN-108516982-A | Method for preparing rifampicin by using microchannel reaction device | 南京工业大学 | 2018-09-11 | — | — | CN | disclosed |
| CN-106749326-A | Method for continuously producing and preparing rifampicin from rifamycin S sodium salt | 南京工业大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-106632394-A | Method for preparing rifampicin by using kettle type reaction device and microchannel reaction device for series reaction | 南京工业大学 | 2017-05-10 | — | — | CN | disclosed |
| CN-103951677-B | The preparation method of rifapentine | SICHUAN LONG MARCH PHARMACEUTICAL CO., LTD. (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-103951677-B | The preparation method of rifapentine | SICHUAN LONG MARCH PHARMACEUTICAL CO., LTD. (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-103951677-A | Preparation method of rifapentine | SICHUAN LONG MARCH PHARMACEUTICAL CO LTD | 2014-07-30 | — | — | CN | disclosed |
| CN-101486716-B | Preparation of rifampin | LI XUE | 2011-01-26 | — | — | CN | disclosed |
| CN-101486716-A | Preparation of good quality benemicin | LI XUE (CN) | 2009-07-22 | — | — | CN | disclosed |
| CN-100383143-C | One-pot processing method for synthesizing rifampicin | LI XUE (CN) | 2008-04-23 | — | — | CN | disclosed |
| CN-1690059-A | One-pot processing method for synthesizing rifampicin | XUE LI (CN) | 2005-11-02 | — | — | CN | disclosed |