Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.56 |
| ▸ | MMP1 | P03956 | 5/20 | 0.54 |
| ▸ | MMP2 | P08253 | 5/20 | 0.54 |
| ▸ | MMP3 | P08254 | 5/20 | 0.54 |
| ▸ | MMP7 | P09237 | 5/20 | 0.54 |
| ▸ | MMP9 | P14780 | 5/20 | 0.54 |
| ▸ | MMP13 | P45452 | 5/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976052 | 0.82 | CAPN1 (0.56) | CAPN1MMP1MMP2MMP3MMP7 | |
| SCHEMBL3840645 | 0.82 | CAPN1 (0.56) | CAPN1MMP1MMP2MMP3MMP7 | |
| SCHEMBL27475768 | 0.82 | CAPN1 (0.56) | CAPN1MMP1MMP2MMP3MMP7 | |
| SCHEMBL3904669 | 0.81 | CAPN1 (0.66) | CAPN1MMP1MMP2MMP3MMP7 | |
| SCHEMBL6026500 | 0.81 | CAPN1 (0.66) | CAPN1MMP1MMP2MMP3MMP7 | |
| SCHEMBL1907361 | 0.81 | CAPN1 (0.66) | CAPN1MMP1MMP2MMP3MMP7 | |
| SCHEMBL5363846 | 0.81 | CAPN1 (0.66) | CAPN1MMP1MMP2MMP3MMP7 | |
| SCHEMBL3913553 | 0.81 | CAPN1 (0.66) | CAPN1MMP1MMP2MMP3MMP7 | |
| SCHEMBL3906288 | 0.77 | MMP1 (0.60) | CAPN1MMP1MMP2MMP3MMP7 | |
| SCHEMBL3840253 | 0.74 | CAPN1 (0.51) | CAPN1MMP1MMP2MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100360117-C | Pharmaceutical composition with improved dissolution | TRANSFORM PHARMACEUTICALS INC (US) | 2008-01-09 | — | — | CN | disclosed |
| CN-1668283-A | Pharmaceutical composition with improved dissolution | TRANSFORM PHARMACEUTICALS INC (US) | 2005-09-14 | — | — | CN | disclosed |