Psilocin

Psilocin

SCHEMBL2761560

CN(C)CCc1c[nH]c2cccc(O)c12.CN(C)CCc1c[nH]c2ccccc12

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 12/20 0.86
HTR2C P28335 11/20 0.86
HTR2B P41595 9/20 0.86
HTR1A P08908 8/20 0.86
HTR6 P50406 4/20 0.86
HTR1B P28222 2/20 0.86
HTR7 P34969 2/20 0.86
HTR5A P47898 2/20 0.86
DRD1 P21728 1/20 0.86
HTR1D P28221 1/20 0.86
HTR1E P28566 1/20 0.86
ADORA2A P29274 1/20 0.86
ADORA2B P29275 1/20 0.86
DRD3 P35462 1/20 0.86
ADRA2A P08913 1/20 0.64
ADRA2B P18089 1/20 0.64
ADRA2C P18825 1/20 0.64
MAOA P21397 1/20 0.64
ADRA1D P25100 1/20 0.64
CHRNB4 P30926 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Psilocin SCHEMBL27221707 0.93 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1AHTR6
Psilocin SCHEMBL31188168 0.93 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1AHTR6
Psilocin SCHEMBL194899 0.93 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1AHTR6
Psilocin SCHEMBL27169386 0.93 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1AHTR6
Psilocin SCHEMBL29363508 0.93 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1AHTR6
Psilocin SCHEMBL25193368 0.92 HTR2A (0.97) HTR2AHTR2CHTR2BHTR1AHTR6
Psilocin SCHEMBL26646472 0.88 HTR2A (0.89) HTR2AHTR2CHTR2BHTR1AHTR6
N,N-Dimethyltryptamine SCHEMBL335710 0.87 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1AHTR6
N,N-Dimethyltryptamine SCHEMBL29350959 0.87 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1AHTR6
N,N-Dimethyltryptamine SCHEMBL27221709 0.87 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010151258-A1 METHODS OF TREATING PSYCHOLOGICAL CONDITIONS THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2010-12-29 WO disclosed