Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20582868 | 0.86 | ALDH1A1 (0.44) | KDM4EALDH1A1GAAHPGDCA2 | |
| SCHEMBL29497677 | 0.86 | ALDH1A1 (0.44) | KDM4EALDH1A1GAAHPGDCA2 | |
| SCHEMBL2296280 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1GAAHPGDCA2 | |
| SCHEMBL6901293 | 0.75 | ALDH1A1 (0.41) | KDM4EALDH1A1GAAHPGDCA2 | |
| SCHEMBL27798969 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1GAAHPGDPPARG | |
| SCHEMBL29497731 | 0.70 | ALDH1A1 (0.42) | KDM4EALDH1A1GAAHPGDPPARG | |
| SCHEMBL20582864 | 0.70 | ALDH1A1 (0.42) | KDM4EALDH1A1GAAHPGDPPARG | |
| SCHEMBL18978960 | 0.69 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAHPGDCA2 | |
| SCHEMBL29497689 | 0.69 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAHPGDCA2 | |
| SCHEMBL24987673 | 0.68 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135350-A2 | BIPHENYL INTERMEDIATE COMPOUNDS AND METHODS FOR THE PREPARATION OF A DUAL ANGIOTENSIN II AND ENDOTHELIN A RECEPTOR ANTAGONIST | PHARMACOPEIA, LLC (US) | 2010-11-25 | — | — | WO | disclosed |