SCHEMBL27616751

SCHEMBL27616751

COc1cccc(C(=O)OBr)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.67
CES1 P23141 1/20 0.67
PARP1 P09874 1/20 0.62
ESR1 P03372 1/20 0.61
ESR2 Q92731 1/20 0.61
SMN1; SMN2 Q16637 4/20 0.56
TP53 P04637 2/20 0.56
NPC1 O15118 5/20 0.56
RAB9A P51151 4/20 0.56
MEN1 O00255 6/20 0.54
KMT2A Q03164 6/20 0.54
PRSS1 P07477 1/20 0.53
PRSS2 P07478 1/20 0.53
PRSS3 P35030 1/20 0.53
ABCG2 Q9UNQ0 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ALDH1A1 P00352 1/20 0.53
PKM P14618 1/20 0.53
HPGD P15428 1/20 0.53
MAPK1 P28482 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl 3-Methoxybenzoate SCHEMBL29702092 0.85 SMN1; SMN2 (0.73) CES2CES1PARP1ESR1ESR2
Methyl 3-Methoxybenzoate SCHEMBL384913 0.85 SMN1; SMN2 (0.73) CES2CES1PARP1ESR1ESR2
SCHEMBL447346 0.85 CES2 (0.71) CES2CES1PARP1ESR1ESR2
SCHEMBL30393680 0.85 CES2 (0.71) CES2CES1PARP1ESR1ESR2
SCHEMBL23509 0.85 CES2 (0.71) CES2CES1PARP1ESR1ESR2
SCHEMBL1356540 0.83 PARP1 (0.70) CES2CES1PARP1ESR1ESR2
SCHEMBL1116172 0.82 ATM (0.46) CES2CES1PARP1SMN1; SMN2TP53
SCHEMBL8190990 0.81 CES2 (0.67) CES2CES1PARP1ESR1ESR2
SCHEMBL6970519 0.81 CES2 (0.67) CES2CES1PARP1ESR1ESR2
SCHEMBL17629345 0.81 PARP1 (0.68) CES2CES1PARP1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1724597-A Phase change inks XEROX CORP (US) 2006-01-25 CN disclosed