Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.55 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.55 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.55 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.55 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.55 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27635716 | 1.00 | GRIK1 (0.55) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL3277307 | 0.83 | SLC7A5 (0.60) | GRIA2SLC7A5PTGS1KDM4EUSP2 | |
| SCHEMBL3279504 | 0.83 | SLC7A5 (0.60) | GRIA2SLC7A5PTGS1KDM4EUSP2 | |
| SCHEMBL3277300 | 0.83 | SLC7A5 (0.60) | GRIA2SLC7A5PTGS1KDM4EUSP2 | |
| SCHEMBL22444711 | 0.83 | GRIK1 (0.53) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8767597 | 0.79 | SLC7A5 (0.50) | SLC7A5PTGS1KDM4EUSP2EGFR | |
| SCHEMBL7774192 | 0.79 | SLC7A5 (0.50) | SLC7A5PTGS1KDM4EUSP2EGFR | |
| SCHEMBL12988571 | 0.77 | KIF11 (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL29567931 | 0.77 | KIF11 (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL5342823 | 0.77 | KIF11 (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1708492-A | Selected CGRP antagonists, method for production and use thereof as medicament | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-12-14 | — | — | CN | disclosed |