Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653938 | 0.86 | L3MBTL1 (0.65) | L3MBTL1CREBBPKDREPHB4NAMPT | |
| SCHEMBL11826508 | 0.83 | L3MBTL1 (0.61) | L3MBTL1KDRNAMPTFEN1 | |
| SCHEMBL21596023 | 0.83 | L3MBTL1 (0.61) | L3MBTL1CREBBPKDREPHB4NAMPT | |
| SCHEMBL13757017 | 0.83 | L3MBTL1 (0.61) | L3MBTL1CREBBPKDREPHB4NAMPT | |
| SCHEMBL12528608 | 0.83 | L3MBTL1 (0.61) | L3MBTL1CREBBPKDREPHB4NAMPT | |
| SCHEMBL11825597 | 0.80 | L3MBTL1 (0.57) | L3MBTL1CREBBPNAMPT | |
| SCHEMBL6030409 | 0.80 | L3MBTL1 (0.62) | L3MBTL1CREBBPKDREPHB4NAMPT | |
| SCHEMBL2641177 | 0.80 | L3MBTL1 (0.57) | L3MBTL1CREBBPKDREPHB4NAMPT | |
| SCHEMBL2641179 | 0.80 | L3MBTL1 (0.57) | L3MBTL1CREBBPKDREPHB4NAMPT | |
| SCHEMBL102258 | 0.79 | L3MBTL1 (0.56) | L3MBTL1CREBBPKDREPHB4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100509833-C | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2009-07-08 | — | — | CN | claimed |
| CN-1630661-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2005-06-22 | — | — | CN | claimed |
| CN-101289483-B | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG | 2012-06-20 | — | — | CN | disclosed |
| CN-101367854-B | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG | 2010-12-29 | — | — | CN | disclosed |
| CN-100509833-C | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2009-07-08 | — | — | CN | disclosed |
| CN-101367854-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2009-02-18 | — | — | CN | disclosed |
| CN-101289484-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2008-10-22 | — | — | CN | disclosed |
| CN-101289483-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2008-10-22 | — | — | CN | disclosed |
| CN-1630661-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2005-06-22 | — | — | CN | disclosed |