Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | CA6 | P23280 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5841574 | 0.92 | ALOX15 (0.59) | ALOX15ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5841870 | 0.91 | ALOX15 (0.58) | ALOX15ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5842336 | 0.91 | ALOX15 (0.58) | ALOX15ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL27617636 | 0.90 | ALOX15 (0.55) | ALOX15ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5841918 | 0.90 | ALOX15 (0.57) | ALOX15ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5841837 | 0.90 | ALOX15 (0.57) | ALOX15ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5842600 | 0.89 | ALOX15 (0.62) | ALOX15ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5844178 | 0.88 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL27617750 | 0.88 | ALOX15 (0.54) | ALOX15ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL27617638 | 0.86 | ALOX15 (0.52) | ALOX15ALDH1A1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100534990-C | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS LTD (CH) | 2009-09-02 | — | — | CN | claimed |
| CN-1610678-A | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS LTD (CH) | 2005-04-27 | — | — | CN | claimed |
| CN-100534990-C | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS LTD (CH) | 2009-09-02 | — | — | CN | disclosed |
| CN-1610678-A | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS LTD (CH) | 2005-04-27 | — | — | CN | disclosed |