Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ASPH | Q12797 | 2/20 | 0.52 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27618224 | 0.94 | VNN1 (0.68) | VNN1ALDH1A1KDM4EASPHKDM8 | |
| Malonic Acid SCHEMBL27637392 | 0.93 | VNN1 (0.63) | VNN1ALDH1A1KDM4EASPHKDM8 | |
| SCHEMBL27429524 | 0.91 | VNN1 (0.61) | VNN1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL27618142 | 0.88 | VNN1 (0.60) | VNN1ALDH1A1KDM4EASPHKDM8 | |
| SCHEMBL18286268 | 0.78 | VNN1 (1.00) | VNN1ALDH1A1 | |
| Acetic Acid SCHEMBL27637267 | 0.77 | ACACB (0.49) | VNN1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL19422706 | 0.77 | KDM4E (0.58) | VNN1KDM4EASPHKDM8FFAR1 | |
| SCHEMBL5622343 | 0.76 | VNN1 (0.59) | VNN1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL18286271 | 0.75 | VNN1 (1.00) | VNN1 | |
| SCHEMBL11563704 | 0.73 | VNN1 (0.64) | VNN1KDM4EASPHKDM8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100551916-C | New 2,4-diamino-1,3,5-triazines derivative | HAMARI CHEMICALS LTD (JP) | 2009-10-21 | — | — | CN | disclosed |
| CN-1726199-A | Novel 2,4-diamino-1,3,5-triazine derivative | HAMARI CHEMICALS LTD (JP) | 2006-01-25 | — | — | CN | disclosed |