Hexanoate

Hexanoate

SCHEMBL2761809

CCCCCC(=O)[O-].CC[N+](CC)(CC)CCOC

nearest known ligand 0.55

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.47
FABP3 P05413 7/20 0.46
NFKB1 P19838 1/20 0.45
BBOX1 O75936 2/20 0.44
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41
GPR84 Q9NQS5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptanoate SCHEMBL2762370 0.98 FABP3 (0.49) CA1FABP3NFKB1BBOX1CES2
Valeric Acid SCHEMBL146021 0.95 CA1 (0.53) CA1FABP3NFKB1BBOX1CES2
Butyric Acid SCHEMBL145420 0.88 FFAR3 (0.52) CA1NFKB1BBOX1CES2CES1
Hexanoate SCHEMBL2761987 0.85 CA1 (0.46) CA1FABP3NFKB1BBOX1CES2
Hexanoate SCHEMBL2762333 0.85 BBOX1 (0.61) CA1FABP3NFKB1BBOX1CES2
Hexanoate SCHEMBL2762073 0.85 BBOX1 (0.61) CA1FABP3NFKB1BBOX1
Dodecanoate SCHEMBL2762624 0.84 BBOX1 (0.59) CA1FABP3BBOX1CES2CES1
Decanoic Acid SCHEMBL2762392 0.84 BBOX1 (0.59) CA1FABP3BBOX1CES2CES1
Dodecanoate SCHEMBL2762115 0.84 BBOX1 (0.59) CA1FABP3BBOX1CES2CES1
Dodecanoate SCHEMBL2761981 0.84 BBOX1 (0.59) CA1FABP3BBOX1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010136105-A2 AMMONIUMCARBOXYLATES MERCK PATENT GMBH (DE) 2010-12-02 WO claimed
WO-2010136105-A2 AMMONIUMCARBOXYLATES MERCK PATENT GMBH (DE) 2010-12-02 WO disclosed