Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAMP1 | O60894 | 1/20 | 0.42 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459960 | 1.00 | RAMP1 (0.42) | RAMP1CALCRLPPARAARHDAC1 | |
| SCHEMBL4459964 | 1.00 | RAMP1 (0.42) | RAMP1CALCRLPPARAARHDAC1 | |
| SCHEMBL3314145 | 0.90 | RAMP1 (0.40) | RAMP1CALCRLPPARAARHDAC1 | |
| SCHEMBL3314330 | 0.85 | PPARA (0.38) | RAMP1CALCRLPPARAARHDAC1 | |
| SCHEMBL3314325 | 0.85 | PPARA (0.38) | RAMP1CALCRLPPARAARHDAC1 | |
| SCHEMBL3309780 | 0.82 | NAAA (0.40) | PPARAARHDAC1GAAMAPT | |
| SCHEMBL3309774 | 0.82 | NAAA (0.40) | PPARAARHDAC1GAAMAPT | |
| SCHEMBL6332671 | 0.82 | CPA1 (0.47) | PPARA | |
| SCHEMBL28389952 | 0.82 | CPA1 (0.47) | PPARA | |
| SCHEMBL28887254 | 0.82 | CPA1 (0.47) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1708493-A | Selected CGRP antagonists, method for production and use thereof as medicament | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-12-14 | — | — | CN | disclosed |