Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SNCA | P37840 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14372957 | 0.94 | MAPT (0.54) | MAPTGAATDP1HPGDKDM4E | |
| SCHEMBL14127780 | 0.88 | HPGD (0.49) | MAPTGAAHPGDSMN1; SMN2TP53 | |
| SCHEMBL6654706 | 0.85 | MAPK13 (0.64) | MAPTGAATDP1HPGDKDM4E | |
| SCHEMBL15081850 | 0.83 | MAPT (0.65) | MAPTGAATDP1HPGDKDM4E | |
| SCHEMBL24208166 | 0.82 | SKP2 (0.49) | MAPTGAAHPGDSMN1; SMN2TP53 | |
| SCHEMBL1031878 | 0.82 | KMT2A (0.49) | MAPTGAAHPGDSMN1; SMN2TP53 | |
| SCHEMBL27694703 | 0.81 | HTR2A (0.43) | MAPTGAAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL8750639 | 0.81 | BACE1 (0.44) | MAPTGAATDP1HPGDSMN1; SMN2 | |
| SCHEMBL1625053 | 0.80 | MAPT (0.59) | MAPTGAATDP1HPGDKDM4E | |
| SCHEMBL2539187 | 0.79 | TRPV1 (0.58) | MAPTGAATDP1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101024633-B | Tricyclic arylamine monomer and polymers and devices thereof | DOW GLOBAL TECHNOLOGIES INC | 2012-11-07 | — | — | CN | disclosed |
| CN-100516118-C | Tricyclic arylamine monomers, polymers thereof and devices | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-07-22 | — | — | CN | disclosed |
| CN-101024633-A | Tricyclic arylamine monomer and polymers and devices thereof | DOW GLOBAL TECHNOLOGIES INC (US) | 2007-08-29 | — | — | CN | disclosed |
| CN-1729229-A | Tricyclic arylamine monomers, polymers thereof and devices | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-02-01 | — | — | CN | disclosed |