Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127780 | 0.88 | HPGD (0.49) | HPGDSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL1031878 | 0.82 | KMT2A (0.49) | HPGDSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL27619358 | 0.81 | MAPT (0.57) | HPGDSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2539187 | 0.79 | TRPV1 (0.58) | HPGDSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL48879 | 0.78 | HPGD (0.58) | HPGDSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL14127779 | 0.78 | HPGD (0.58) | HPGDSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL24175223 | 0.78 | HSD11B1 (0.47) | HPGDSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL28857667 | 0.78 | HPGD (0.57) | HPGDSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL27694703 | 0.78 | HTR2A (0.43) | HPGDSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| Water SCHEMBL28757114 | 0.78 | TRPV1 (0.57) | HPGDSMN1; SMN2ALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552925-B1 | Equilibration of cyclic siloxanes with catalysts | DOW CORNING (US) | 1997-04-09 | — | — | EP | disclosed |
| EP-0552925-A2 | Equilibration of cyclic siloxanes with novel catalysts | DOW CORNING CORPORATION (US) | 1993-07-28 | — | — | EP | disclosed |