Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27406375 | 0.94 | NAAA (0.68) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL27406374 | 0.94 | NAAA (0.68) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL28203935 | 0.89 | NAAA (0.64) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL27993602 | 0.87 | NAAA (0.61) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL27619584 | 0.86 | NAAA (0.69) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL27687320 | 0.86 | NAAA (0.68) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL27687297 | 0.86 | NAAA (0.68) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL28472074 | 0.86 | NAAA (0.59) | NAAASMN1; SMN2HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL27619603 | 0.85 | NAAA (0.68) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL421014 | 0.85 | NAAA (1.00) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100410236-C | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-1633410-A | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (AN) | 2005-06-29 | — | — | CN | disclosed |