Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744458 | 0.77 | GRM2 (0.31) | GRM2 | |
| SCHEMBL2744441 | 0.77 | KDM4E (0.41) | KDM4EGRM2 | |
| SCHEMBL3176003 | 0.77 | KEAP1 (0.36) | GRM2SMN1; SMN2 | |
| SCHEMBL17524640 | 0.76 | GRM2 (0.32) | KDM4EGRM2 | |
| SCHEMBL4550236 | 0.74 | KDM4E (0.30) | KDM4E | |
| SCHEMBL6835435 | 0.74 | KEAP1 (0.47) | GRM2SMN1; SMN2 | |
| SCHEMBL9801574 | 0.74 | KDM4E (0.34) | KDM4EGRM2 | |
| SCHEMBL3366427 | 0.74 | HSD17B10 (0.46) | KDM4EGRM2GLAJAK2JAK1 | |
| SCHEMBL14167508 | 0.73 | PAOX (0.37) | KDM4EGLASMN1; SMN2GAA | |
| SCHEMBL23254096 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1774435-A | 5-membered heterocyclic derivative | DAIICHI SEIYAKU CO (JP) | 2006-05-17 | — | — | CN | disclosed |
| CN-1759110-A | Pyrazole derivatives | DAIICHI SEIYAKU CO (JP) | 2006-04-12 | — | — | CN | disclosed |