Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592039 | 0.82 | HRH3 (0.63) | ALDH1A1KMT2AMEN1ATMHRH3 | |
| SCHEMBL13727922 | 0.82 | GAA (0.58) | ALDH1A1HRH3HRH4 | |
| SCHEMBL16254956 | 0.82 | GAA (0.58) | ALDH1A1HRH3HRH4 | |
| SCHEMBL25740940 | 0.82 | GAA (0.58) | ALDH1A1HRH3HRH4 | |
| SCHEMBL5048083 | 0.80 | KMT2A (0.63) | ALDH1A1KMT2AMEN1ATMHRH3 | |
| SCHEMBL1823298 | 0.80 | KMT2A (0.63) | ALDH1A1KMT2AMEN1ATMHRH3 | |
| SCHEMBL13726832 | 0.79 | HPGD (0.60) | ALDH1A1KMT2AMEN1HRH3HRH4 | |
| SCHEMBL8244556 | 0.79 | HRH3 (0.54) | ALDH1A1KMT2AMEN1HRH3HRH4 | |
| SCHEMBL82814 | 0.79 | HPGD (0.60) | ALDH1A1KMT2AMEN1HRH3HRH4 | |
| SCHEMBL4592427 | 0.79 | HRH3 (0.64) | ALDH1A1KMT2AMEN1ATMHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1923812-A | New compounds | ASTRAZENECA AB (SE) | 2007-03-07 | — | — | CN | claimed |
| CN-1642938-A | Novel compounds | ASTRAZENECA AB (SE) | 2005-07-20 | — | — | CN | claimed |
| CN-100519550-C | 2-oxoindole compounds having inhibitory activity on glycogen synthase kinase 3 receptor | ASTRAZENECA AB SE (SE) | 2009-07-29 | — | — | CN | disclosed |
| CN-1923812-A | New compounds | ASTRAZENECA AB (SE) | 2007-03-07 | — | — | CN | disclosed |
| CN-1642938-A | Novel compounds | ASTRAZENECA AB (SE) | 2005-07-20 | — | — | CN | disclosed |