Naphthalene

Naphthalene

SCHEMBL27620149

F.Nc1cccc(N)c1C=Cc1ccccc1.c1ccc2ccccc2c1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.48
NFE2L2 Q16236 3/20 0.48
CYP19A1 P11511 2/20 0.48
MAOA P21397 2/20 0.48
RELA Q04206 1/20 0.48
GRM4 Q14833 4/20 0.47
HDAC6 Q9UBN7 2/20 0.41
MAPT P10636 1/20 0.41
ALDH1A1 P00352 4/20 0.40
HPGD P15428 3/20 0.40
KDM4E B2RXH2 3/20 0.40
CYP3A4 P08684 2/20 0.40
TSHR P16473 2/20 0.40
KEAP1 Q14145 1/20 0.40
HSD17B10 Q99714 1/20 0.40
DHFR P00374 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
PKM P14618 2/20 0.39
GRM5 P41594 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27512901 0.92 MAOB (0.56) MAOBNFE2L2CYP19A1MAOAGRM4
Toluene SCHEMBL27930865 0.82 CYP19A1 (0.47) MAOBNFE2L2CYP19A1MAOARELA
SCHEMBL10701359 0.80 NFE2L2 (0.48) MAOBNFE2L2CYP19A1MAOAGRM4
SCHEMBL5873007 0.80 NFE2L2 (0.48) MAOBNFE2L2CYP19A1MAOAGRM4
SCHEMBL29107871 0.78 MAOB (0.47) MAOBNFE2L2CYP19A1MAOAGRM4
SCHEMBL28522905 0.78 MAOB (0.47) MAOBNFE2L2CYP19A1MAOAGRM4
SCHEMBL3922074 0.77 CYP1B1 (0.46) MAOBNFE2L2CYP19A1MAOARELA
SCHEMBL28128701 0.75 CYP19A1 (0.58) MAOBNFE2L2CYP19A1MAOARELA
SCHEMBL6422560 0.73 HPRT1 (0.49) MAOBNFE2L2CYP19A1MAOARELA
(Z)-1,2-Diphenylethene SCHEMBL28006165 0.72 MAOB (0.69) MAOBNFE2L2CYP19A1MAOARELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100478364-C Ethylene polymer and molded article obtained therefrom MITSUI CHEMICALS INC (JP) 2009-04-15 CN disclosed
CN-1732189-A Ethylene polymer and molded article obtained therefrom MITSUI CHEMICALS INC (JP) 2006-02-08 CN disclosed