Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 7/20 | 0.66 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.64 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.42 |
| ▸ | PDE2A | O00408 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29761432 | 0.78 | KCNK3 (1.00) | KCNK3KCNK9KCNA5PDE2A | |
| SCHEMBL498598 | 0.78 | KCNK3 (1.00) | KCNK3KCNK9KCNA5PDE2A | |
| SCHEMBL13801055 | 0.78 | KCNK3 (1.00) | KCNK3KCNK9KCNA5PDE2A | |
| SCHEMBL498597 | 0.78 | KCNK3 (1.00) | KCNK3KCNK9KCNA5PDE2A | |
| SCHEMBL31478899 | 0.75 | KCNK3 (0.61) | KCNK3KCNK9PDE2APOLBKMT2A | |
| Butane SCHEMBL498343 | 0.74 | KCNK3 (0.61) | KCNK3KCNK9PDE2AMEN1POLB | |
| SCHEMBL14498283 | 0.71 | KCNA5 (0.77) | KCNK3KCNK9KCNA5MEN1POLB | |
| SCHEMBL14306639 | 0.69 | KCNK3 (0.55) | KCNK3KCNK9PDE2ASLC8A1 | |
| SCHEMBL13480244 | 0.68 | KCNK3 (0.82) | KCNK3KCNK9KCNA5MEN1KMT2A | |
| SCHEMBL8294602 | 0.67 | KCNK3 (0.81) | KCNK3KCNK9KCNA5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100361943-C | 2-(butyl-1-sulfonylamino)-n-[1(r)-(6-methoxypyridin-3-yl)propyl] benzamide, its use as a medicament, and pharmaceutical preparations comprising it | AVENTIS PHARMA GMBH (DE) | 2008-01-16 | — | — | CN | disclosed |
| CN-1756728-A | 2- (butyl-1-sulfonylamino) -N- [1(R) - (6-methoxypyridin-3-yl) propyl ] benzamide, its use as a medicament and pharmaceutical formulations containing it | AVENTIS PHARMA GMBH (DE) | 2006-04-05 | — | — | CN | disclosed |