Butanol

Butanol

SCHEMBL27620184

CC(C)NC(C)C.CCC(C)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.67
TDP1 Q9NUW8 2/20 0.53
ALDH1A1 P00352 2/20 0.37
ADRB2 P07550 2/20 0.35
PTGS2 P35354 1/20 0.35
OPRK1 P41145 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HSD17B10 Q99714 2/20 0.32
LMNA P02545 2/20 0.31
KDM4E B2RXH2 2/20 0.31
HIF1A Q16665 2/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
BLM P54132 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butanol SCHEMBL1418 0.82
Butanol SCHEMBL55899 0.82
Butanol SCHEMBL2012224 0.82 TSHR (1.00) TSHRTDP1ALDH1A1HSD17B10LMNA
Butanol SCHEMBL55049 0.82
Propylene Glycol SCHEMBL17512355 0.80 TDP1 (0.67) TSHRTDP1ALDH1A1LMNAKDM4E
Butanol SCHEMBL11270518 0.79
Cyclohexane SCHEMBL8727010 0.79 TSHR (0.77) TSHRTDP1ALDH1A1HSD17B10LMNA
Alcohol SCHEMBL1199528 0.79 TDP1 (0.61) TSHRTDP1ALDH1A1LMNAKDM4E
Butanol SCHEMBL1554783 0.78
Butanol SCHEMBL5697609 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1990453-B Process for producing nitrogen-containing compounds KAO CORP 2012-10-03 CN disclosed
CN-1990454-B Process for producing nitrogen-containing compounds KAO CORP 2012-07-25 CN disclosed
CN-100484933-C Novel pyrazine compounds, their use in preparing medicament for treating diseases correlated with serotonin BIOVITRUM AB (SE) 2009-05-06 CN disclosed
CN-1990453-A Process for producing nitrogen-containing compounds KAO CORP (JP) 2007-07-04 CN disclosed
CN-1990454-A Process for producing nitrogen-containing compounds KAO CORP (JP) 2007-07-04 CN disclosed
CN-1662522-A Novel compounds, their use and preparation BIOVITRUM AB (SE) 2005-08-31 CN disclosed