Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL11157385 | 0.85 | TDP1 (0.61) | TDP1TSHR | |
| Alcohol SCHEMBL9949362 | 0.80 | — | — | |
| SCHEMBL28021736 | 0.80 | TDP1 (0.67) | TDP1 | |
| Methyl Alcohol SCHEMBL2170375 | 0.79 | — | — | |
| Hydrogen Peroxide SCHEMBL135017 | 0.79 | TDP1 (0.80) | TDP1ALDH1A1LMNA | |
| Hydrogen Peroxide SCHEMBL135019 | 0.79 | — | — | |
| Propylene Glycol SCHEMBL17512355 | 0.79 | TDP1 (0.67) | TDP1TSHRALDH1A1LMNAKDM4E | |
| Butanol SCHEMBL27620184 | 0.79 | TSHR (0.67) | TDP1TSHRALDH1A1LMNAKDM4E | |
| SCHEMBL27928984 | 0.78 | TDP1 (1.00) | TDP1TSHRALDH1A1 | |
| SCHEMBL2020 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893163-B2 | Gradient copolymers soluble or at least dispersible in water as well as in organic solvents | ARKEMA FRANCE (FR) | 2011-02-22 | — | — | US | disclosed |
| CN-100360543-C | Method for preparing ammonium salts of cyclohexanpentol phosphate ester | UNIV SICHUAN NORMAL (CN) | 2008-01-09 | — | — | CN | disclosed |
| CN-100360544-C | Ammonium salt of cyclohexanpentol and its use | UNIV SICHUAN NORMAL (CN) | 2008-01-09 | — | — | CN | disclosed |
| CN-1830986-A | Method for preparing ammonium salts of cyclohexanpentol phosphate ester | UNIV SICHUAN NORMAL (CN) | 2006-09-13 | — | — | CN | disclosed |
| CN-1830987-A | Ammonium salt of cyclohexanpentol and its use | UNIV SICHUAN NORMAL (CN) | 2006-09-13 | — | — | CN | disclosed |
| US-20060058467-A1 | Gradient copolymers soluble or at least dispersible in water as well as in organic solvents | ARKEMA FRANCE (FR) | 2006-03-16 | — | — | US | disclosed |
| US-5025012-A | Cardiovascular disorders; antiischemic agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-06-18 | — | — | US | disclosed |
| US-5021438-A | Having affinity for 5-hydroxytryptamine receptors; treating central nervous system and cardiovascular disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| US-4421739-A | SUNTAN LOTION | L'OREAL (FR) | 1983-12-20 | — | — | US | disclosed |
| US-4380591-A | POLYESTER URETHANE COPOLYMER | UNION CARBIDE CORPORATION (US) | 1983-04-19 | — | — | US | disclosed |