Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.33 |
| ▸ | PDE8A | O60658 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.31 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27620343 | 0.98 | CYP1A2 (0.33) | CYP1A2ALDH1A1MAPTL3MBTL1S1PR4 | |
| SCHEMBL5541944 | 0.90 | KCNH2 (0.36) | CYP1A2ALDH1A1MAPTL3MBTL1S1PR4 | |
| SCHEMBL27777586 | 0.83 | KDM4E (0.36) | ALDH1A1CCNCCDK8KDM4E | |
| SCHEMBL14680553 | 0.83 | MAPT (0.35) | CYP1A2ALDH1A1MAPTL3MBTL1S1PR4 | |
| Hydrochloric Acid SCHEMBL28293574 | 0.81 | MAPT (0.34) | CYP1A2ALDH1A1MAPTL3MBTL1S1PR4 | |
| SCHEMBL23639466 | 0.77 | CYP1A2 (0.37) | CYP1A2ALDH1A1MAPTL3MBTL1PDE8A | |
| SCHEMBL27667500 | 0.75 | DAO (0.33) | L3MBTL1KDM4E | |
| SCHEMBL5252807 | 0.74 | HRH1 (0.50) | CYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL5541218 | 0.73 | RECQL (0.49) | — | |
| SCHEMBL3363951 | 0.73 | ALDH1A1 (0.38) | CYP1A2ALDH1A1MAPTL3MBTL1PDE8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015636-B | Azetidines and cyclobutanes as histamine H3 receptor antagonists | EVOTEC NEUROSCIENCES GMBH | 2014-08-13 | — | — | CN | disclosed |
| CN-101454311-B | Salt of phenoxypyridine derivative, crystal thereof and process for producing the same | EISAI R&D MAN CO LTD | 2013-03-27 | — | — | CN | disclosed |
| CN-102015636-A | Azetidines and cyclobutanes as histamine H3 receptor antagonists | EVOTEC NEUROSCIENCES GMBH | 2011-04-13 | — | — | CN | disclosed |
| CN-1711347-B | Use of metal complex compounds as oxidation catalysts | CIBA SC HOLDING AG | 2010-05-26 | — | — | CN | disclosed |
| CN-101454311-A | Salt of phenoxypyridine derivative, crystal thereof and process for producing the same | EISAI R&D MAN CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-101163693-A | Antibacterial piperidine derivatives | ASTRAZENECA AB (SE) | 2008-04-16 | — | — | CN | disclosed |
| CN-101098753-A | Use of metal complexes with bispyridylpyrimidine or bispyridyltriazine ligands as catalysts for reactions with peroxides for bleaching coloured stains on hard surfaces | CIBA SC HOLDING AG (CH) | 2008-01-02 | — | — | CN | disclosed |
| CN-1711347-A | Use of metal complex compounds as oxidation catalysts | CIBA SC HOLDING AG (CH) | 2005-12-21 | — | — | CN | disclosed |