Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28323248 | 0.81 | TSHR (0.43) | TSHRHPGDALDH1A1HSD17B10THRB | |
| SCHEMBL10456265 | 0.81 | TSHR (0.43) | TSHRHPGDALDH1A1HSD17B10THRB | |
| SCHEMBL776448 | 0.80 | ALDH1A1 (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| Ammonia Solution, Strong SCHEMBL29418168 | 0.78 | ALDH1A1 (0.38) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL29116626 | 0.77 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8952938 | 0.77 | ALDH1A1 (0.40) | TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL10823142 | 0.77 | ALDH1A1 (0.36) | TSHRALDH1A1TDP1 | |
| SCHEMBL10823143 | 0.77 | ALDH1A1 (0.36) | TSHRALDH1A1TDP1 | |
| SCHEMBL28730235 | 0.76 | TSHR (0.34) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27847517 | 0.76 | ALDH1A1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1756765-A | Metastin derivative and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-04-05 | — | — | CN | disclosed |