Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | GGT1 | P19440 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620450 | 0.85 | GRIK1 (0.41) | BLMCA2MAPK1CA1 | |
| SCHEMBL27620513 | 0.82 | GGT1 (0.37) | BLMARG1ARG2GGT1NOS1 | |
| SCHEMBL264732 | 0.82 | GGT1 (0.42) | BLMARG1ARG2GGT1NOS1 | |
| SCHEMBL27601822 | 0.82 | GGT1 (0.42) | BLMARG1ARG2GGT1NOS1 | |
| SCHEMBL27601885 | 0.81 | CACNA2D1 (0.40) | BLMARG1ARG2GGT1NOS1 | |
| SCHEMBL27620443 | 0.81 | BLM (0.48) | BLMARG1ARG2GGT1NOS1 | |
| Hydrochloric Acid SCHEMBL28437650 | 0.80 | GGT1 (0.41) | BLMARG1ARG2GGT1NOS1 | |
| Hydrochloric Acid SCHEMBL4330886 | 0.80 | GGT1 (0.41) | BLMARG1ARG2GGT1NOS1 | |
| Benzene SCHEMBL4960434 | 0.78 | GGT1 (0.39) | BLMARG1ARG2GGT1NOS1 | |
| Benzene SCHEMBL27719900 | 0.78 | GGT1 (0.39) | BLMARG1ARG2GGT1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | claimed |
| CN-1653036-A | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2005-08-10 | — | — | CN | claimed |
| CN-100462351-C | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2009-02-18 | — | — | CN | disclosed |
| CN-1856301-A | Curable beta-amino acid | WARNER LAMBERT CO (US) | 2006-11-01 | — | — | CN | disclosed |
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1653036-A | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2005-08-10 | — | — | CN | disclosed |