⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29014782 | 1.00 | — | — | |
| SCHEMBL4409122 | 0.80 | — | — | |
| SCHEMBL6601988 | 0.80 | — | — | |
| SCHEMBL23227487 | 0.78 | — | — | |
| SCHEMBL18306102 | 0.74 | CHRNB2 (0.36) | — | |
| SCHEMBL18305953 | 0.74 | CHRNB2 (0.36) | — | |
| SCHEMBL28693616 | 0.74 | USP2 (0.33) | — | |
| SCHEMBL17585530 | 0.72 | — | — | |
| SCHEMBL14827980 | 0.72 | — | — | |
| SCHEMBL3144405 | 0.71 | USP2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109419802-B | Compounds having dopamine D3 receptor modulating activity and uses thereof | 中国人民解放军军事医学科学院毒物药物研究所（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-102264733-A | novel dopamine D3 receptor ligand, preparation method and medical application thereof | — | 2011-11-30 | — | — | CN | disclosed |
| CN-1639135-A | N-aryl-2-oxazolidinone-5-amides and derivatives thereof and their use as antibacterial agents | UPJOHN CO (US) | 2005-07-13 | — | — | CN | disclosed |