Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688386 | 0.85 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL17067672 | 0.83 | TSHR (0.56) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL16327 | 0.83 | TSHR (0.56) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL8861475 | 0.81 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL10064134 | 0.81 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL23607574 | 0.81 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL5053935 | 0.81 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL8861451 | 0.81 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL9079087 | 0.81 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL10657311 | 0.81 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100475798-C | Sulfonate derivatives and the use therof as latent acids | CIBA SC HOLDING AG (CH) | 2009-04-08 | — | — | CN | disclosed |
| CN-1628268-A | Sulfonic acid derivatives and their use as latent acids | CIBA SC HOLDING AG (CH) | 2005-06-15 | — | — | CN | disclosed |