Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | DAO | P14920 | 1/20 | 0.67 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.67 |
| ▸ | CES1 | P23141 | 5/20 | 0.56 |
| ▸ | CES2 | O00748 | 3/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1681320 | 1.00 | TSHR (0.67) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL9563651 | 1.00 | TSHR (0.67) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL2411132 | 1.00 | TSHR (0.67) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL8432316 | 1.00 | TSHR (0.67) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL11031846 | 1.00 | TSHR (0.67) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL2356436 | 1.00 | TSHR (0.67) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL11490240 | 0.90 | TSHR (0.63) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL8506032 | 0.90 | TSHR (0.63) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL2687529 | 0.90 | TSHR (0.63) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL1785542 | 0.88 | TSHR (0.52) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260051539-A1 | SECONDARY BATTERY AND ELECTRONIC DEVICE | NINGDE AMPEREX TECHNOLOGY LIMITED (CN) | 2026-02-19 | — | — | US | claimed |
| EP-4697429-A2 | SECONDARY BATTERY AND ELECTRONIC DEVICE | NINGDE AMPEREX TECHNOLOGY LIMITED (CN) | 2026-02-18 | — | — | EP | claimed |
| CN-119674246-A | Secondary battery and electronic device | 宁德新能源科技有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-118645696-B | Secondary battery and electronic device | 宁德新能源科技有限公司 | 2025-01-24 | — | — | CN | claimed |
| EP-4294646-B1 | SECURITY ELEMENT AND METHOD FOR PRODUCING SAME | GIESECKE & DEVRIENT CURRENCY TECHNOLOGY GMBH (DE) | 2024-10-23 | — | — | EP | claimed |
| US-20240308264-A1 | SECURITY ELEMENT AND METHOD FOR PRODUCING SAME | GIESECKE+DEVRIENT CURRENCY TECHNOLOGY GMBH (DE) | 2024-09-19 | — | — | US | claimed |
| CN-118652532-A | Low-VOC high-antistatic deformation rapid recovery thermoplastic polyether ester elastomer composite material, preparation method thereof and 3D hollow fiber structure | 会通新材料股份有限公司 | 2024-09-17 | — | — | CN | claimed |
| CN-118645696-A | Secondary battery and electronic device | 宁德新能源科技有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-118599295-A | High-melting high-resilience antistatic thermoplastic polyether ester elastomer material, preparation method thereof and high-permeability 3D hollow fiber structure with excellent low-pressure-variation fatigue resistance durability | 会通新材料股份有限公司 | 2024-09-06 | — | — | CN | claimed |
| CN-118440471-A | Scratch-resistant wear-resistant matte thermoplastic polyether ester elastomer rubber coating composition and preparation method thereof | 会通新材料(上海)有限公司 | 2024-08-06 | — | — | CN | claimed |
| US-4349503-A | CRYSTALLIZATION; SODIUM NITRITE AS A NUCLEATING AGENT | ALLIED CORPORATION (US) | 1982-09-14 | — | — | US | claimed |
| US-4348497-A | AUTOMOBILE ENAMELS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | claimed |
| WO-1982002400-A1 | ACRYLIC RESIN WITH ANTIPLASTICIZER | DU PONT (US) | 1982-07-22 | — | — | WO | claimed |
| US-4304808-A | HEAT SENSITIVE COMPRISING METAL, ACRYLIC HOT MELT ADHESIVE, PLASTICIZER AND SOLVENT; DECALCOMANIA | JOHNSON, MATTHEY & CO., LIMITED (GB) | 1981-12-08 | — | — | US | claimed |
| US-RE30696-E | COMPRISING AN ESTER OF A POLYHYDRIC ALCOHOL, AN ACID, AN ACTIVATOR, AND A HARDENER; PRINTED CIRCUITS | MULTICORE SOLDERS LIMITED (GB) | 1981-08-04 | — | — | US | claimed |
| US-4259225-A | STORAGE STABILITY | DAINIPPON INK & CHEMICALS, INC. (JP) | 1981-03-31 | — | — | US | claimed |
| US-4243440-A | ESTER OF POLYHYDRIC ALCOHOL, ROSIN ESTER | MULTICORE SOLDERS LIMITED (GB) | 1981-01-06 | — | — | US | claimed |
| US-4117182-A | ALIPHATIC OXYALKYLATED ALCOHOL, HEAT ACTIVATABLE ADHESIVE | COMMERCIAL DECAL, INC. (US) | 1978-09-26 | — | — | US | claimed |
| US-4068033-A | Heat-releasable decalcomanias and adhesive composition therefor | COMMERCIAL DECAL, INC. (US) | 1978-01-10 | — | — | US | claimed |
| US-4018728-A | PIGMENTARY MATERIALS, HOT MELT ADHESIVES, PLASTICIZER AND SOLVENT | JOHNSON MATTHEY & CO., LIMITED (EN) | 1977-04-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260051539-A1 | SECONDARY BATTERY AND ELECTRONIC DEVICE | TESK2, TESK1, CACNA2D4 | TSHR 877/4885DAO 934/4885NAPRT 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.