Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | TACR2 | P21452 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SHBG | P04278 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | TST | Q16762 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728741 | 1.00 | ESR1 (0.57) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL10892112 | 1.00 | ESR1 (0.57) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL1789902 | 0.94 | ESR1 (0.57) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL10884228 | 0.91 | ESR1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL11847647 | 0.90 | DGKA (0.62) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL31539532 | 0.88 | TRPV1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL16681273 | 0.88 | DGKA (0.64) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL15015438 | 0.88 | DGKA (0.64) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL9252939 | 0.88 | ESR1 (0.57) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL10840858 | 0.87 | TDP1 (0.58) | ESR1ADRA2AADORA3TACR2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100582086-C | Compound towards target of cardiac muscle and preparation | UNIV SHENYANG PHARMACEUTICAL | 2010-01-20 | — | — | CN | claimed |
| CN-1660780-A | Compound towards target of cardiac muscle and preparation | UNIV SHENYANG PHARMACY (CN) | 2005-08-31 | — | — | CN | claimed |
| CN-100582086-C | Compound towards target of cardiac muscle and preparation | UNIV SHENYANG PHARMACEUTICAL | 2010-01-20 | — | — | CN | disclosed |
| CN-1660780-A | Compound towards target of cardiac muscle and preparation | UNIV SHENYANG PHARMACY (CN) | 2005-08-31 | — | — | CN | disclosed |