Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 10/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426003 | 0.80 | CYP2D6 (0.44) | CYP2D6CTSASRCLMNAMAPK1 | |
| SCHEMBL4805668 | 0.74 | CTSA (0.42) | CTSALMNA | |
| SCHEMBL474256 | 0.74 | SMN1; SMN2 (0.48) | CTSALMNA | |
| SCHEMBL7824501 | 0.72 | CYP2D6 (0.76) | CYP2D6SRCLMNAMAPK1CES1 | |
| SCHEMBL9030789 | 0.72 | CTSA (0.46) | CTSACES1 | |
| SCHEMBL4327553 | 0.71 | CTSA (0.41) | CTSA | |
| SCHEMBL20773271 | 0.70 | CTSA (0.39) | CTSA | |
| SCHEMBL1803210 | 0.70 | DPP4 (0.38) | CTSA | |
| SCHEMBL4004965 | 0.70 | TSHR (0.38) | CTSALMNA | |
| SCHEMBL4341896 | 0.70 | CTSA (0.38) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1747731-A | Imidazopyridines containing combinations and their use in treating gastrointestinal inflammatory disorders | ALTANA PHARMA AG (DE) | 2006-03-15 | — | — | CN | claimed |