Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4123938 | 0.87 | PTGDR2 (0.63) | PTGDR2LMNASMN1; SMN2 | |
| SCHEMBL4123944 | 0.83 | LMNA (0.66) | PTGDR2LMNASMN1; SMN2 | |
| SCHEMBL4129242 | 0.83 | LMNA (0.66) | PTGDR2LMNASMN1; SMN2 | |
| SCHEMBL27622502 | 0.81 | PTGDR2 (0.56) | PTGDR2LMNASMN1; SMN2 | |
| SCHEMBL6289374 | 0.80 | PTGDR2 (0.55) | PTGDR2LMNASMN1; SMN2 | |
| SCHEMBL6070644 | 0.78 | PTGDR2 (0.70) | PTGDR2 | |
| SCHEMBL6070649 | 0.78 | PTGDR2 (0.70) | PTGDR2 | |
| SCHEMBL5319959 | 0.78 | PTGDR2 (0.70) | PTGDR2 | |
| SCHEMBL6420229 | 0.78 | PTGDR2 (0.70) | PTGDR2 | |
| SCHEMBL4128957 | 0.78 | PTGDR2 (0.67) | PTGDR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1720047-A | PgD2 receptor antagonists for the treatment of inflammatory diseases | MILLENNIUM PHARM INC (US) | 2006-01-11 | — | — | CN | claimed |