Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27622726 | 0.90 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL27622647 | 0.87 | SMN1; SMN2 (0.48) | MEN1KMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL27622709 | 0.84 | BLM (0.40) | MEN1KMT2ASMN1; SMN2LMNARAB9A | |
| SCHEMBL28748244 | 0.83 | MAPT (0.51) | MEN1KMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL28755120 | 0.83 | SMN1; SMN2 (0.40) | MEN1KMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL28752419 | 0.83 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL27603880 | 0.83 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL5835296 | 0.79 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL5831228 | 0.76 | MEN1 (0.59) | MEN1KMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL27622655 | 0.75 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1649855-A | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2005-08-03 | — | — | CN | claimed |
| CN-1649855-A | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2005-08-03 | — | — | CN | disclosed |