Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 4/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27622700 | 0.88 | CSNK2A2 (0.40) | BLMHPNSULT1A1CSNK2A2CSNK2A1 | |
| SCHEMBL27604035 | 0.86 | ATM (0.42) | BLMHPNCSNK2A2CSNK2A1ALDH1A1 | |
| SCHEMBL28748244 | 0.84 | MAPT (0.51) | ALDH1A1MEN1GAAKMT2AKDM4E | |
| SCHEMBL27622657 | 0.84 | MEN1 (0.48) | ALDH1A1MEN1GAAKMT2AKDM4E | |
| SCHEMBL28755206 | 0.83 | CA1 (0.39) | BLMHPNCSNK2A2CSNK2A1ALDH1A1 | |
| SCHEMBL27604137 | 0.82 | PIM1 (0.39) | BLMCSNK2A2CSNK2A1ALDH1A1MEN1 | |
| SCHEMBL5832259 | 0.78 | ALDH1A1 (0.52) | BLMHPNCSNK2A2CSNK2A1ALDH1A1 | |
| SCHEMBL5831178 | 0.74 | ATM (0.51) | BLMHPNCSNK2A2CSNK2A1ALDH1A1 | |
| SCHEMBL27622707 | 0.74 | AKT1 (0.41) | BLMHPNSULT1A1CSNK2A2CSNK2A1 | |
| SCHEMBL27622726 | 0.74 | MEN1 (0.52) | ALDH1A1MEN1GAAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1649855-A | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2005-08-03 | — | — | CN | claimed |
| CN-1649855-A | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2005-08-03 | — | — | CN | disclosed |