Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 6/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 4/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885884 | 0.82 | KIT (0.54) | KITACHEALDH1A1 | |
| SCHEMBL794385 | 0.78 | HTT (0.46) | HTTKITPIK3CAMTORKDM4E | |
| SCHEMBL794742 | 0.78 | HTT (0.73) | HTTKITKDM4EGAAAKT1 | |
| SCHEMBL23932500 | 0.72 | MAPT (0.41) | HTTKITPIK3CAMTORKDM4E | |
| SCHEMBL7063580 | 0.71 | KIT (0.47) | HTTKITAKT1PDGFRBMAPK1 | |
| SCHEMBL5278122 | 0.70 | LMNA (0.67) | HTTAKT1PDGFRB | |
| SCHEMBL3884555 | 0.70 | FLT3 (0.44) | KITAKT1PDGFRB | |
| SCHEMBL3644224 | 0.70 | LIMK2 (0.63) | AKT1 | |
| SCHEMBL29247593 | 0.70 | LIMK2 (0.42) | KITAKT1PDGFRB | |
| SCHEMBL25173918 | 0.70 | MAPT (0.40) | HTTKITPIK3CAMTORKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1745080-A | 1,3-dihydroimidazole fused-ring compound | EISAI CO LTD (JP) | 2006-03-08 | — | — | CN | disclosed |