Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18171779 | 0.90 | ALDH1A1 (0.64) | ALDH1A1KDM4ETSHRNPC1GAA | |
| SCHEMBL7734714 | 0.82 | ALDH1A1 (0.81) | ALDH1A1KDM4ETSHRGAASMN1; SMN2 | |
| SCHEMBL15826887 | 0.82 | SMN1; SMN2 (0.71) | ALDH1A1KDM4ETSHRNPC1GAA | |
| SCHEMBL3571941 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRNPC1GAA | |
| SCHEMBL19420852 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4ETSHRNPC1GAA | |
| SCHEMBL19410130 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1GAAAPEX1 | |
| SCHEMBL2762171 | 0.79 | APEX1 (0.79) | ALDH1A1KDM4ENPC1GAAAPEX1 | |
| Hydrochloric Acid SCHEMBL19410134 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4ENPC1GAAAPEX1 | |
| SCHEMBL7746061 | 0.78 | HDAC1 (0.53) | ALDH1A1SMN1; SMN2MAPTPOLBTP53 | |
| SCHEMBL18171837 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1GAAAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142616-A2 | DEPROTECTION OF BOC-PROTECTED COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-16 | — | — | WO | disclosed |
| US-20100311968-A1 | DEPROTECTION OF BOC-PROTECTED COMPOUNDS | CHOY JASON CHI-CHUNG | 2010-12-09 | — | — | US | disclosed |