Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 9/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28093204 | 0.92 | MGAM (0.43) | SMN1; SMN2EPHX1NAAAMGAMGAA | |
| SCHEMBL1734362 | 0.88 | EPHX1 (0.46) | SMN1; SMN2EPHX1NAAAMEN1MAPT | |
| SCHEMBL27842415 | 0.86 | EPHX1 (0.49) | SMN1; SMN2EPHX1NAAAMEN1MAPT | |
| SCHEMBL28150044 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2EPHX1NAAAASAH1 | |
| SCHEMBL28020725 | 0.83 | MGAM (0.35) | SMN1; SMN2NAAAMGAMGAASI | |
| SCHEMBL25022401 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2EPHX1NAAAMEN1MAPT | |
| SCHEMBL20954311 | 0.81 | LMNA (0.55) | EPHX1NAAAMGAMGAASI | |
| SCHEMBL8894777 | 0.80 | EPHX1 (0.42) | SMN1; SMN2EPHX1NAAAGAAALDH1A1 | |
| SCHEMBL11880421 | 0.80 | EPHX1 (0.44) | SMN1; SMN2EPHX1NAAAMEN1MAPT | |
| SCHEMBL29171649 | 0.80 | MGAM (0.39) | SMN1; SMN2EPHX1NAAAMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1711263-A | 5-alkyl-7-aminotriazolopyrimidines, methods and intermediary product necessary for the production thereof, agents containing said compounds and the use thereof for fighting against harmful mushrooms | BASF AG (DE) | 2005-12-21 | — | — | CN | disclosed |
| CN-1655778-A | Methods of treating hepatitis C virus infection using pyranoindole derivatives | WYETH CORP (US) | 2005-08-17 | — | — | CN | disclosed |