Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27624291 | 0.96 | PIN1 (0.45) | MRGPRX4MAOBNR4A2PIN1FFAR1 | |
| SCHEMBL27624313 | 0.88 | MRGPRX4 (0.46) | MRGPRX4MAOBNR4A2PTGER4FFAR4 | |
| SCHEMBL27624307 | 0.86 | MRGPRX4 (0.44) | MRGPRX4MAOBNR4A2FFAR1PTGER4 | |
| SCHEMBL28752675 | 0.85 | MRGPRX4 (0.46) | MRGPRX4MAOBNR4A2PTGER4FFAR4 | |
| SCHEMBL27624319 | 0.84 | BAZ2B (0.39) | FABP3FABP4FABP5 | |
| SCHEMBL27624321 | 0.83 | FFAR1 (0.40) | MRGPRX4FABP3FABP4FABP5FFAR1 | |
| SCHEMBL27605315 | 0.80 | NPC1 (0.38) | — | |
| SCHEMBL3982596 | 0.79 | PPARG (0.51) | MRGPRX4MAOBNR4A2FABP3FABP4 | |
| SCHEMBL3978466 | 0.77 | PPARG (0.51) | MRGPRX4MAOBNR4A2PIN1FFAR1 | |
| SCHEMBL27605306 | 0.76 | MAPT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100543022-C | 2-furancarboxylic acid hydrazide compound and contain the pharmaceutical composition of this compound | DAINIPPON PHARMACEUTICAL CO (JP) | 2009-09-23 | — | — | CN | disclosed |
| CN-1628111-A | 2-furancarboxylic acid hydrazides and pharmaceutical compositions containing the same | DAINIPPON PHARMACEUTICAL CO (JP) | 2005-06-15 | — | — | CN | disclosed |