Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 5/20 | 0.48 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605321 | 0.89 | MRGPRX4 (0.55) | NR1H4MAOBMRGPRX4NR4A2 | |
| SCHEMBL3973274 | 0.88 | NR1H4 (0.51) | NR1H4MAOAMAOBFFAR1PPARD | |
| SCHEMBL27624290 | 0.86 | FFAR1 (0.54) | MAOAMAOBFFAR1SLC16A3 | |
| SCHEMBL27605323 | 0.81 | MEN1 (0.52) | MAOBFFAR1HDAC8 | |
| SCHEMBL27624301 | 0.77 | ESR1 (0.52) | MAOBFFAR1MRGPRX4NR4A2 | |
| SCHEMBL3975306 | 0.77 | SMPD1 (0.49) | NR1H4MAOBMRGPRX4HDAC4NR4A2 | |
| SCHEMBL3975736 | 0.77 | NR1H4 (0.45) | NR1H4 | |
| SCHEMBL27624296 | 0.76 | KMO (0.50) | HDAC1HDAC8HDAC6 | |
| SCHEMBL3975374 | 0.76 | GCGR (0.62) | NR1H4 | |
| SCHEMBL3974918 | 0.74 | ESR1 (0.42) | FFAR1MRGPRX4PPARGNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100543022-C | 2-furancarboxylic acid hydrazide compound and contain the pharmaceutical composition of this compound | DAINIPPON PHARMACEUTICAL CO (JP) | 2009-09-23 | — | — | CN | disclosed |
| CN-1628111-A | 2-furancarboxylic acid hydrazides and pharmaceutical compositions containing the same | DAINIPPON PHARMACEUTICAL CO (JP) | 2005-06-15 | — | — | CN | disclosed |