Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.36 |
| ▸ | MME | P08473 | 5/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31510814 | 0.85 | ACE (0.42) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL313185 | 0.83 | ACE (0.41) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL6552340 | 0.83 | KDM4E (0.54) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL3714795 | 0.83 | KDM4E (0.54) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL15375770 | 0.81 | CHRM1 (0.44) | ACEFOLH1MMENAALAD2ALDH1A1 | |
| SCHEMBL5940872 | 0.81 | CHRM1 (0.44) | ACEFOLH1MMENAALAD2ALDH1A1 | |
| SCHEMBL3836127 | 0.81 | CHRM1 (0.44) | ACEFOLH1MMENAALAD2ALDH1A1 | |
| SCHEMBL3836129 | 0.81 | CHRM1 (0.44) | ACEFOLH1MMENAALAD2ALDH1A1 | |
| SCHEMBL27767453 | 0.81 | CHRM1 (0.44) | ACEFOLH1MMENAALAD2ALDH1A1 | |
| SCHEMBL19521363 | 0.80 | ACE (0.39) | ACEKDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1756562-A | Influenza virus vaccine | MERCK & CO INC (US) | 2006-04-05 | — | — | CN | disclosed |