SCHEMBL3714795

SCHEMBL3714795

CC(NC(CS)C(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.54
MAPT P10636 1/20 0.54
THRB P10828 1/20 0.54
ALOX15 P16050 1/20 0.54
NFKB1 P19838 1/20 0.54
PTGS2 P35354 1/20 0.54
THPO P40225 1/20 0.54
RECQL P46063 1/20 0.54
BLM P54132 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
ACE P12821 2/20 0.53
FOLH1 Q04609 3/20 0.41
MME P08473 5/20 0.38
NAALAD2 Q9Y3Q0 2/20 0.38
ENPEP Q07075 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CPA1 P15085 1/20 0.37
ACE2 Q9BYF1 1/20 0.37
PTGS1 P23219 1/20 0.36
SLC7A11 Q9UPY5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6552340 1.00 KDM4E (0.54) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL25761663 0.84 KDM4E (0.56) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL1058215 0.84 KDM4E (0.56) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL1058214 0.84 KDM4E (0.56) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL28854052 0.84 KDM4E (0.56) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL27624628 0.83 ACE (0.41) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL23552453 0.82 KDM4E (0.54) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL313275 0.82 KDM4E (0.54) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL7259700 0.82 ACE (0.59) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL107698 0.80 KDM4E (0.52) KDM4EMAPTTHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1106657-A Pharmaceutical composition for maintaining and/or reestablishing a near normal blood platelet aggregarion rate MARTHE DEHORNE (FR) 1995-08-16 CN claimed
EP-0645138-A2 Pharmaceutical composition for maintaining and/or reestablishing a rate of blood platelet aggregation clone to the normal value Dehorne, Marthe (FR) 1995-03-29 EP claimed
EP-0483261-A1 HIRUDIN PEPTIDE DERIVATIVES BIOGEN, INC. (US) 1992-05-06 EP claimed
WO-1991001328-A1 HIRUDIN PEPTIDE DERIVATIVES BIOGEN, INC. (US) 1991-02-07 WO claimed
CN-118833937-B Polyamine-based furnace water treatment agent and preparation method and application method thereof 南京顺水达环保科技有限公司 2025-02-28 CN disclosed
CN-118833937-A Polyamine-based furnace water treatment agent and preparation method and application method thereof 南京顺水达环保科技有限公司 2024-10-25 CN disclosed
WO-2010111789-A1 INHIBITION OF FORMATION OF ADVANCED GLYCATION ENDPRODUCTS UNIVERSITY OF SASKATCHEWAN (CA) 2010-10-07 WO disclosed
CN-1756562-A Influenza virus vaccine MERCK & CO INC (US) 2006-04-05 CN disclosed
EP-1179612-B1 Process for the electrochemical reduction of organic compounds. CONSORTIUM ELEKTROCHEM IND (DE) 2004-02-11 EP disclosed
US-6669828-B2 For the electrochemical reduction of organic compounds Consortium für elektrochemische Industrie GmbH (DE) 2003-12-30 US disclosed
US-20020027083-A1 For the electrochemical reduction of organic compounds CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH 2002-03-07 US disclosed
EP-1179612-A1 Cathode for electrolytic cells Consortium für elektrochemische Industrie GmbH (DE) 2002-02-13 EP disclosed
CN-1106657-A Pharmaceutical composition for maintaining and/or reestablishing a near normal blood platelet aggregarion rate MARTHE DEHORNE (FR) 1995-08-16 CN disclosed
EP-0645138-A2 Pharmaceutical composition for maintaining and/or reestablishing a rate of blood platelet aggregation clone to the normal value Dehorne, Marthe (FR) 1995-03-29 EP disclosed