SCHEMBL27624907

SCHEMBL27624907

CCCCOc1cncc(OCCCC)c1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.52
CYP2C19 P33261 3/20 0.52
CYP1A2 P05177 2/20 0.52
MCHR1 Q99705 3/20 0.45
TLR8 Q9NR97 3/20 0.45
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
AOC3 Q16853 4/20 0.44
LOX P28300 2/20 0.42
CYP2D6 P10635 5/20 0.41
CYP3A4 P08684 4/20 0.41
CDC7 O00311 1/20 0.40
ROCK2 O75116 1/20 0.40
MAP4K4 O95819 1/20 0.40
PIM1 P11309 1/20 0.40
PRKACA P17612 1/20 0.40
CDK2 P24941 1/20 0.40
GSK3B P49841 1/20 0.40
HIPK2 Q9H2X6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27645054 0.89 ALDH1A1 (0.46) CYP2C9CYP2C19CYP1A2MCHR1TLR8
SCHEMBL27624877 0.82 AOC3 (0.63) TLR8KDM4ENPC1RAB9AAOC3
SCHEMBL7921354 0.76 CYP1A2 (0.70) CYP2C9CYP2C19CYP1A2MCHR1TLR8
SCHEMBL9912721 0.75 CYP2C9 (0.58) CYP2C9CYP2C19CYP1A2MCHR1TLR8
SCHEMBL19141233 0.74 CYP1A2 (0.52) CYP2C9CYP2C19CYP1A2MCHR1TLR8
SCHEMBL15871998 0.74 PDE4A (0.37) CYP2C9CYP2C19CYP1A2MCHR1TLR8
SCHEMBL7546340 0.72 CYP1A2 (0.50) CYP2C9CYP2C19CYP1A2MCHR1TLR8
SCHEMBL16248313 0.72 HTR1B (0.50) CYP2C9CYP2C19CYP1A2MCHR1TLR8
SCHEMBL27645080 0.72 CYP2C9 (0.50) CYP2C9CYP2C19CYP1A2MCHR1TLR8
SCHEMBL26781479 0.72 AOC3 (0.46) CYP2C9CYP2C19CYP1A2AOC3LOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100340560-C N,N'-dipyridyl-equibenzyl-tetraformyldiimine derivative and its synthesis method UNIV SOUTHEAST (CN) 2007-10-03 CN claimed
CN-100340558-C N,N-dipyridyl 3,4,9,10-tetraformyl diimine derirative and its synthesis method UNIV DONGNAN (CN) 2007-10-03 CN claimed
CN-1785998-A N,N-dipyridyl 3,4,9,10-tetraformyl diimine derirative and its synthesis method UNIV DONGNAN (CN) 2006-06-14 CN claimed
CN-1763041-A N,N'-dipyridyl-equibenzyl-tetraformyldiimine derivative and its synthesis method UNIV SOUTHEAST (CN) 2006-04-26 CN claimed
CN-100340560-C N,N'-dipyridyl-equibenzyl-tetraformyldiimine derivative and its synthesis method UNIV SOUTHEAST (CN) 2007-10-03 CN disclosed
CN-100340558-C N,N-dipyridyl 3,4,9,10-tetraformyl diimine derirative and its synthesis method UNIV DONGNAN (CN) 2007-10-03 CN disclosed
CN-1785998-A N,N-dipyridyl 3,4,9,10-tetraformyl diimine derirative and its synthesis method UNIV DONGNAN (CN) 2006-06-14 CN disclosed
CN-1763041-A N,N'-dipyridyl-equibenzyl-tetraformyldiimine derivative and its synthesis method UNIV SOUTHEAST (CN) 2006-04-26 CN disclosed