Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL3901610 | 0.86 | LMNA (0.43) | ALOX5EPHX1CYP2D6HPGDKMT2A | |
| SCHEMBL2904004 | 0.82 | CHRM5 (0.43) | EPHX1KMT2ANOS1NOS2 | |
| SCHEMBL3222970 | 0.82 | CHRM5 (0.43) | EPHX1KMT2ANOS1NOS2 | |
| SCHEMBL6533680 | 0.82 | CHRM5 (0.43) | EPHX1KMT2ANOS1NOS2 | |
| SCHEMBL1930290 | 0.82 | CHRM5 (0.43) | EPHX1KMT2ANOS1NOS2 | |
| SCHEMBL11006113 | 0.82 | CHRM5 (0.43) | EPHX1KMT2ANOS1NOS2 | |
| SCHEMBL23070439 | 0.82 | CHRM5 (0.43) | EPHX1KMT2ANOS1NOS2 | |
| SCHEMBL6532715 | 0.82 | CHRM5 (0.43) | EPHX1KMT2ANOS1NOS2 | |
| SCHEMBL187659 | 0.82 | CHRM5 (0.43) | EPHX1KMT2ANOS1NOS2 | |
| SCHEMBL1524658 | 0.82 | CHRM5 (0.43) | EPHX1KMT2ANOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516346-B | Submicron nanoparticles of water-insoluble camptothecin derivatives and methods of making same | SAMYANG CORP | 2012-05-23 | — | — | CN | disclosed |
| CN-101516346-A | Submicron nanoparticles of water-insoluble camptothecin derivatives and methods of making same | SAMYANG CORP (KR) | 2009-08-26 | — | — | CN | disclosed |
| CN-100471886-C | Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery | SAMYANG CORP (KR) | 2009-03-25 | — | — | CN | disclosed |
| CN-1780865-A | Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery | SAMYANG CORP (KR) | 2006-05-31 | — | — | CN | disclosed |