Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 6/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3350783 | 0.78 | HCAR3 (0.42) | CRHR1HCAR3MAPTSMN1; SMN2HPGD | |
| SCHEMBL1179427 | 0.73 | HCRTR1 (0.43) | CRHR1HCAR3SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL27625566 | 0.72 | TDP1 (0.47) | CRHR1HCAR3MAPTSMN1; SMN2HPGD | |
| SCHEMBL988811 | 0.72 | TDP1 (0.38) | CRHR1HTTALDH1A1KDM4ETDP1 | |
| SCHEMBL3350110 | 0.72 | MAPT (0.41) | CRHR1MAPTSMN1; SMN2HPGDHTT | |
| SCHEMBL13034403 | 0.71 | SLC29A1 (0.45) | MAPTSMN1; SMN2HPGDCASP1HTT | |
| SCHEMBL12871103 | 0.71 | TDP1 (0.44) | CRHR1MAPTSMN1; SMN2HPGDCASP1 | |
| SCHEMBL27625587 | 0.70 | FFAR1 (0.43) | MAPTSMN1; SMN2HPGDHTTALDH1A1 | |
| SCHEMBL11448126 | 0.70 | KDM4E (0.45) | MAPTSMN1; SMN2HPGDHTTALDH1A1 | |
| SCHEMBL30349506 | 0.70 | KDM4E (0.45) | MAPTSMN1; SMN2HPGDHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1759095-A | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARM INC (US) | 2006-04-12 | — | — | CN | disclosed |