Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | SPNS2 | Q8IVW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27627059 | 0.95 | TLR8 (0.54) | TLR8ALDH1A1POLBKMT2AKCNH2 | |
| SCHEMBL3865520 | 0.94 | TLR8 (0.53) | TLR8ALDH1A1POLBKMT2AKCNH2 | |
| SCHEMBL10532493 | 0.94 | TLR8 (0.53) | TLR8ALDH1A1POLBKMT2AKCNH2 | |
| SCHEMBL10530747 | 0.94 | TLR8 (0.53) | TLR8ALDH1A1POLBKMT2AKCNH2 | |
| SCHEMBL1075831 | 0.93 | ALDH1A1 (0.54) | TLR8ALDH1A1POLBKMT2AKCNH2 | |
| Bromide SCHEMBL1029841 | 0.92 | ALDH1A1 (0.53) | TLR8ALDH1A1POLBKMT2AKCNH2 | |
| Hydrochloric Acid SCHEMBL1029443 | 0.92 | ALDH1A1 (0.53) | TLR8ALDH1A1POLBKMT2AKCNH2 | |
| SCHEMBL22356840 | 0.92 | TLR8 (0.49) | TLR8ALDH1A1POLBKMT2AKCNH2 | |
| SCHEMBL17219025 | 0.92 | TLR8 (0.49) | TLR8ALDH1A1POLBKMT2AKCNH2 | |
| SCHEMBL1049122 | 0.90 | ALDH1A1 (0.61) | TLR8ALDH1A1POLBKMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026092-A | Imidazo [4,5-c] cycle compound of guanidine substitution | 3M创新有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-101687867-B | Imidazoquinolines with immuno-modulating properties | ASTRAZENECA AB | 2013-10-02 | — | — | CN | disclosed |
| CN-1812789-B | Sulfonamide substituted imidazoquinolines | 3M INNOVATION CO LTD | 2010-07-14 | — | — | CN | disclosed |
| CN-101687867-A | imidazoquinolines with immuno-modulating properties | ASTRAZENECA AB | 2010-03-31 | — | — | CN | disclosed |
| CN-1812789-A | Sulfonamide substituted imidazoquinolines | 3M INNOVATION CO LTD (US) | 2006-08-02 | — | — | CN | disclosed |