Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25527598 | 0.85 | SMN1; SMN2 (0.54) | ALDH1A1L3MBTL1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL135355 | 0.81 | L3MBTL1 (0.66) | ALDH1A1L3MBTL1HPGDMAPTSMN1; SMN2 | |
| Trimethylammonium SCHEMBL27818073 | 0.79 | TSHR (0.57) | ALDH1A1L3MBTL1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL25645639 | 0.79 | L3MBTL1 (0.64) | ALDH1A1L3MBTL1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL8675027 | 0.79 | L3MBTL1 (0.64) | ALDH1A1L3MBTL1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL11011562 | 0.78 | L3MBTL1 (0.62) | ALDH1A1L3MBTL1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL6724547 | 0.78 | TSHR (0.55) | ALDH1A1L3MBTL1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL11177908 | 0.78 | L3MBTL1 (0.62) | ALDH1A1L3MBTL1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL10921665 | 0.78 | L3MBTL1 (0.62) | ALDH1A1L3MBTL1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL10921663 | 0.78 | L3MBTL1 (0.62) | ALDH1A1L3MBTL1HPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101787000-B | M-stage kinesin inhibitor | KYOWA HAKKO KOGYO KK | 2011-08-03 | — | — | CN | disclosed |
| CN-101787000-A | M-stage kinesin inhibitor | KYOWA HAKKO KOGYO KK | 2010-07-28 | — | — | CN | disclosed |
| CN-1774428-B | M-phase kinesin inhibitors | KYOWA HAKKO KOGYO KK | 2010-06-16 | — | — | CN | disclosed |
| CN-1774428-A | M-phase kinesin inhibitors | KYOWA HAKKO KOGYO KK (JP) | 2006-05-17 | — | — | CN | disclosed |