Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 4/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | EGFR | P00533 | 1/20 | 0.67 |
| ▸ | CSF1R | P07333 | 1/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.67 |
| ▸ | FLT1 | P17948 | 1/20 | 0.67 |
| ▸ | FLT4 | P35916 | 1/20 | 0.67 |
| ▸ | KDR | P35968 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 16/20 | 0.66 |
| ▸ | BRAF | P15056 | 3/20 | 0.51 |
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038122 | 0.87 | FLT1 (0.75) | KITABL1EGFRCSF1RPDGFRB | |
| SCHEMBL2489551 | 0.83 | ABL1 (0.78) | KITABL1EGFRCSF1RPDGFRB | |
| SCHEMBL3866257 | 0.82 | KIT (0.76) | KITABL1EGFRCSF1RPDGFRB | |
| SCHEMBL3865996 | 0.82 | ABL1 (0.76) | KITABL1EGFRCSF1RPDGFRB | |
| SCHEMBL5900627 | 0.81 | ABL1 (0.72) | KITABL1EGFRCSF1RPDGFRB | |
| SCHEMBL29356168 | 0.81 | KDR (1.00) | KITABL1EGFRCSF1RPDGFRB | |
| SCHEMBL4976103 | 0.81 | KDR (1.00) | KITABL1EGFRCSF1RPDGFRB | |
| SCHEMBL15528722 | 0.80 | RXFP1 (1.00) | KITABL1EGFRCSF1RPDGFRB | |
| SCHEMBL27608465 | 0.80 | ALDH1A1 (0.47) | KITBRAF | |
| SCHEMBL3864360 | 0.79 | KIT (0.69) | KITABL1EGFRCSF1RPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1671666-A | VEGFR-2 and VEGFR-3 inhibitory anthranilamide pyridine compounds | SCHERING AG (DE) | 2005-09-21 | — | — | CN | disclosed |