SCHEMBL27628010

SCHEMBL27628010

[CH2]C(O)n1c2ccccc2c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.54
DNM1 Q05193 4/20 0.43
GPR3 P46089 1/20 0.42
TSHR P16473 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
POLB P06746 2/20 0.41
NPY1R P25929 1/20 0.41
NPY2R P49146 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
RECQL P46063 1/20 0.41
KDM4E B2RXH2 2/20 0.39
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HRH1 P35367 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22325589 0.76 GPR3 (0.48) BACE1DNM1GPR3TSHRCYP1A2
SCHEMBL4615211 0.76 BACE1 (0.48) BACE1DNM1GPR3TSHRCYP1A2
SCHEMBL4789763 0.76 BACE1 (0.44) BACE1DNM1GPR3TSHRCYP1A2
SCHEMBL14948496 0.74 GPR3 (0.50) BACE1DNM1GPR3TSHRCYP1A2
SCHEMBL11788366 0.71 BACE1 (0.48) BACE1DNM1GPR3TSHRCYP1A2
SCHEMBL29780042 0.70 BCHE (0.59) BACE1GPR3TSHRCYP1A2CYP2C19
SCHEMBL4000759 0.70 GPR3 (0.46) BACE1DNM1GPR3TSHRCYP1A2
SCHEMBL14048485 0.70 GPR3 (0.46) BACE1GPR3TSHRCYP1A2CYP2C19
SCHEMBL15615581 0.70 GPR3 (0.46) BACE1DNM1GPR3TSHRCYP1A2
SCHEMBL150044 0.70 BCHE (0.59) BACE1GPR3TSHRCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100412060-C Prepn of-2-(N-carbazolyl)-ethoxy carbohydrazide DALIAN CHEMICAL PHYSICS INST (CN) 2008-08-20 CN disclosed
CN-1810789-A Prepn of-2-(N-carbazolyl)-ethoxy carbohydrazide DALIAN CHEMICAL PHYSICS INST (CN) 2006-08-02 CN disclosed