Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829956 | 0.85 | PTPRA (0.65) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7829954 | 0.85 | PTPRA (0.65) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5862097 | 0.83 | EPHX1 (0.60) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10764744 | 0.83 | PTPRA (0.57) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25214176 | 0.79 | PTPRA (0.53) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6203944 | 0.76 | EPHX1 (0.65) | PTPN1SMN1; SMN2ALDH1A1MITFHTT | |
| SCHEMBL27608839 | 0.76 | PTPN1 (0.57) | CYP1A1CYP19A1PTPN1ALDH1A1 | |
| Lanicemine SCHEMBL8779512 | 0.76 | GRIN2D (0.77) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| Lanicemine SCHEMBL8779477 | 0.76 | GRIN2D (0.77) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27543486 | 0.74 | PTPRA (0.50) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |