Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 12/20 | 0.64 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27608839 | 0.88 | PTPN1 (0.57) | EPHX1PTPN1MDM2ALDH1A1PTPN2 | |
| SCHEMBL6203634 | 0.88 | NTSR1 (0.57) | EPHX1PTPN1MDM2L3MBTL1LMNA | |
| SCHEMBL29240046 | 0.87 | PTPN1 (0.59) | EPHX1PTPN1MDM2LMNAHSD17B10 | |
| SCHEMBL29240033 | 0.84 | PTPN1 (0.67) | EPHX1PTPN1PTPN2 | |
| SCHEMBL547425 | 0.84 | PTPN1 (0.56) | EPHX1PTPN1MDM2LMNAHSD17B10 | |
| SCHEMBL2922282 | 0.84 | MITF (0.59) | PTPN1L3MBTL1LMNAMITFALDH1A1 | |
| SCHEMBL27628032 | 0.84 | CHRM1 (0.60) | EPHX1PTPN1TDP1LMNAHTT | |
| SCHEMBL27683344 | 0.84 | PTPN1 (0.50) | EPHX1PTPN1MDM2MITFALDH1A1 | |
| SCHEMBL6327117 | 0.83 | PTPN1 (0.55) | PTPN1L3MBTL1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL67234 | 0.82 | EPHX1 (0.71) | EPHX1UBE2NCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107903158-B | Synthesis method of 1,2, 3-triphenylpropyl-1-ketone | 郑州大学 | 2020-07-31 | — | — | CN | claimed |
| CN-107903158-B | Synthesis method of 1,2, 3-triphenylpropyl-1-ketone | 郑州大学 | 2020-07-31 | — | — | CN | disclosed |
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |
| EP-1115729-B1 | PHOSPHONIC ACID DERIVATIVES AS INHIBITORS OF PTP-1B | MERCK FROSST CANADA INC (CA) | 2003-02-19 | — | — | EP | disclosed |
| US-6174874-B1 | ANTIDIABETIC,-CARCINOGENIC AGENTS; IMPROVING GLUCOSE TOLERANCE/INSULIN-SENSITIVITY; PREVENTING/TREATING OBESITY AND NEURODEGENERATIVE DISEASES; E.G. 1,3-BIS-((PHOSPHONODI-FLUOROMETHYL)PHENYL)-2-DICARBOXYPROPANE | MERCK FROSST CANADA & CO. (CA) | 2001-01-16 | — | — | US | disclosed |