SCHEMBL276281

SCHEMBL276281

C(=Cc1ccc(-n2c3ccccc3c3ccccc32)cc1)c1ccc(N(c2ccccc2)c2ccc3c(c2)c2ccccc2n3-c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
ATM Q13315 2/20 0.49
APP P05067 1/20 0.40
RELA Q04206 1/20 0.35
MEN1 O00255 5/20 0.34
KMT2A Q03164 5/20 0.34
POLB P06746 4/20 0.34
KLK7 P49862 1/20 0.34
PKM P14618 1/20 0.34
HTT P42858 1/20 0.34
MAPK8 P45983 1/20 0.33
HDAC4 P56524 1/20 0.33
ALDH1A1 P00352 3/20 0.33
USP2 O75604 2/20 0.33
MAPT P10636 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
TLR9 Q9NR96 1/20 0.33
GAA P10253 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL276280 1.00 KDM4E (0.49) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL31268435 0.99 KDM4E (0.50) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL3033494 0.99 KDM4E (0.50) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL36256 0.99 KDM4E (0.50) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL36257 0.99 KDM4E (0.50) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL1981041 0.97 KDM4E (0.49) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL1981042 0.97 KDM4E (0.49) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL10123661 0.94 ATM (0.41) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL12163943 0.92 KDM4E (0.44) KDM4EL3MBTL1ATMAPPMEN1
SCHEMBL10123640 0.92 KDM4E (0.44) KDM4EL3MBTL1ATMAPPRELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9174927-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-03 US disclosed
US-20140225097-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-14 US disclosed
US-8704215-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-04-22 US disclosed
US-20120168741-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-07-05 US disclosed
US-8134148-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-13 US disclosed
US-20100301322-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-12-02 US disclosed
US-7732619-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-08 US disclosed
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device NR2E3, NR0B2, NR0B1 KDM4E 3249/4885L3MBTL1 2886/4885ATM 2454/4885
US-20140225097-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device NR2E3, NR0B2, NR0B1 KDM4E 3249/4885L3MBTL1 2886/4885ATM 2454/4885
US-20120168741-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device NR2E3, NR0B2, NR0B1 KDM4E 3249/4885L3MBTL1 2886/4885ATM 2454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.