Chlorobenzene

Chlorobenzene

SCHEMBL27628409

Clc1ccccc1.Nc1ncnc(Cl)n1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.47
SLC6A2 P23975 1/20 0.47
PDE4A P27815 1/20 0.47
KDR P35968 1/20 0.47
BCL6 P41182 2/20 0.46
TSHR P16473 1/20 0.44
ADORA2A P29274 3/20 0.41
ADORA1 P30542 2/20 0.41
KCNH2 Q12809 1/20 0.41
SCN5A Q14524 1/20 0.41
SCN9A Q15858 1/20 0.41
LMNA P02545 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GLA P06280 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GRM4 Q14833 1/20 0.38
HTT P42858 1/20 0.38
DHFR P00374 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370381 0.85
SCHEMBL154798 0.85
Hydrochloric Acid SCHEMBL27782884 0.83
Trifluoromethylbenzene SCHEMBL27850302 0.80 KDM4E (0.48) ADORA3SLC6A2PDE4AKDRBCL6
Benzene SCHEMBL29138620 0.72 BCL6 (0.52) ADORA3SLC6A2PDE4AKDRBCL6
Propylamine SCHEMBL15720251 0.72 ADORA3 (0.36) ADORA3SLC6A2PDE4AKDRBCL6
Aniline SCHEMBL28021586 0.72 TSHR (0.55) ADORA3BCL6TSHRADORA2AADORA1
Biphenyl SCHEMBL27987857 0.72 ADORA2A (0.56) ADORA3BCL6ADORA2AADORA1KDM4E
Chlorobenzene SCHEMBL10939803 0.72 TSHR (0.55) TSHRLMNAKDM4EALDH1A1GLA
Chlorobenzene SCHEMBL27640363 0.70 TSHR (0.69) TSHRLMNAKDM4EALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100417324-C Compsn. of agricultural pesticide and preparation method UNIV BEIJING CHEMICAL (CN) 2008-09-10 CN disclosed
CN-1695446-A Compsn. of agricultural pesticide and preparation method UNIV BEIJING CHEMICAL (CN) 2005-11-16 CN disclosed